Histones
H3K4me1
H3K4me3
H3K27ac
Opposes H3K27me3
Since the H3K27ac and H3K27me3 modification is at the same location on the histone tail, they antagonize each other.[15] H3K27ac is often used to find active enhancers and poised enhancers subtracting from another enhancer mark H3K4me1 that contains all enhancers
Backlinks
- Malladi_2020: Total functional score of enhancer elements identifies lineage-specific enhancers that drive differentiation of pancreatic cells
- Mikkelsen_2007: Genome-wide maps of chromatin state in pluripotent and lineage-committed cells
- Sartorelli_2020: Enhancer RNAs are an important regulatory layer of the epigenome