TODO Chromatin Looping
Chromatin can loop, which is thought to be caused by the enhancer-promoter interaction.
Can be validated by assays such as Hi-C
The looping may cause micro-fluid environments that create droplets.
TODO Chromatin State
- Single-cell epigenomics reveals mechanisms of human cortical development : (Ziffra_2021)
- Malladi_2020: Total functional score of enhancer elements identifies lineage-specific enhancers that drive differentiation of pancreatic cells
- Minnoye_2021: Chromatin accessibility profiling methods
- Sartorelli_2020: Enhancer RNAs are an important regulatory layer of the epigenome
- BIOL5420 - Molecular Biology
- /cis/-regulatory elements